The most common symptom of Gilbert's syndrome is mild episodes of jaundice (yellowing of the skin and the whites of the eyes) that comes and goes.
The yellowing of the skin may be less noticeable if you have brown or black skin, but it may be easier to see jaundice in the white part of your eyes.
Jaundice can also cause itchy skin, darker pee and paler poo than usual. However, Gilbert's syndrome does not usually cause these symptoms, which means the jaundice is likely to be caused by something else.
Ask for an urgent GP appointment or get help from NHS 111 if:
- you think you have jaundice and you have not been diagnosed with Gilbert's syndrome
- you've been diagnosed with Gilbert's syndrome and the jaundice is worse than usual, or it does not go away within a few days
You can call 111 or get help from 111 online.
Gilbert's syndrome can be diagnosed with blood tests, including a test to check how well your liver is working.
A genetic test is sometimes needed to confirm the diagnosis.
As Gilbert's syndrome may not cause any symptoms, some people only find out they have it during tests for something else.
You will not need any medical treatment for Gilbert's syndrome as it does not usually cause any serious health problems.
However, there are things you can try to help prevent jaundice.
Do
keep a record of your jaundice and try to avoid things that trigger it – for example, over-exercising, not getting enough sleep, drinking alcohol or not drinking enough fluids
speak to a GP or pharmacist before taking any new medicines – you may need to be more closely monitored while taking certain medicines, such as statins for high cholesterol
Gilbert's syndrome is caused by an altered gene being passed on to a child by their parents (inherited).
This affects your liver and causes a substance called bilirubin to build up in your bloodstream. This can turn your skin and the whites of your eyes yellow.
Gilbert's syndrome is more common in men and people with type 1 diabetes.
There is currently no cure for Gilbert's syndrome, but it does not cause any damage to your liver and does not usually cause any serious health problems.
It does not affect how long you'll live.
You may have a slightly increased risk of gallstones, but it does not increase your risk of any other conditions.
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19 May 2026
